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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1688 All Species: 16.06
Human Site: Y186 Identified Species: 44.17
UniProt: Q9C0H5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9C0H5 NP_079527.1 1083 121286 Y186 L E K D Y E I Y R D Y S A D G
Chimpanzee Pan troglodytes XP_520025 1126 126113 Y186 L E K D Y E I Y R D Y S A D G
Rhesus Macaque Macaca mulatta XP_001095036 1083 121236 Y186 L E K D Y E I Y R D Y S A D G
Dog Lupus familis XP_539224 1015 113288 S180 V S R E G S T S S S L E P E L
Cat Felis silvestris
Mouse Mus musculus P59281 1107 125188 Y182 L E K D Y E V Y R D Y S A D G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417317 1381 150829 K470 L Q E M E R G K G D C A A D R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007296 1067 119680 A179 Q P S P G S K A A M L V K V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392788 1054 119503 N179 L E L E K N K N G R E S S R G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798334 1348 153268 S254 Q G Q P P N F S R Y P T H G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 98.9 75.2 N.A. 86.9 N.A. N.A. N.A. 33.9 N.A. 42.1 N.A. N.A. 27.5 N.A. 26.7
Protein Similarity: 100 95.1 99.6 79.4 N.A. 90.8 N.A. N.A. N.A. 46.9 N.A. 56.1 N.A. N.A. 43.7 N.A. 40.1
P-Site Identity: 100 100 100 0 N.A. 93.3 N.A. N.A. N.A. 26.6 N.A. 0 N.A. N.A. 26.6 N.A. 13.3
P-Site Similarity: 100 100 100 26.6 N.A. 100 N.A. N.A. N.A. 46.6 N.A. 0 N.A. N.A. 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 12 12 0 0 12 56 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % C
% Asp: 0 0 0 45 0 0 0 0 0 56 0 0 0 56 0 % D
% Glu: 0 56 12 23 12 45 0 0 0 0 12 12 0 12 0 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 0 23 0 12 0 23 0 0 0 0 12 67 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 45 0 12 0 23 12 0 0 0 0 12 0 0 % K
% Leu: 67 0 12 0 0 0 0 0 0 0 23 0 0 0 12 % L
% Met: 0 0 0 12 0 0 0 0 0 12 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 23 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 23 12 0 0 0 0 0 12 0 12 0 0 % P
% Gln: 23 12 12 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 12 0 0 12 0 0 56 12 0 0 0 12 12 % R
% Ser: 0 12 12 0 0 23 0 23 12 12 0 56 12 0 12 % S
% Thr: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % T
% Val: 12 0 0 0 0 0 12 0 0 0 0 12 0 12 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 45 0 0 45 0 12 45 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _